Baumann Group

Team members | Projects | Publications | Completed Theses

We develop optical technology for imaging the eye and brain

Our research is focused on the development of optical imaging technology and its application for biomedical imaging. Our current research is driven by the need for better and more reliable methods for medical diagnostics as well as by the desire to understand basic biological and medical research questions. Our recent research projects include the development of optical imaging - in particular optical coherence tomography (OCT), functional and multi-contrast OCT imaging, multi-modal optical imaging and microscopy, and applied preclinical imaging in longitudinal studies of ophthalmic and neurological disease models.

Research Area

Biophotonics

Research Topics

OCT Technologies | Translational OCT | Advanced Microscopy & Spectroscopy | Multimodal Biomedical Imaging

Team members

From left to right: P. Eugui, B. Hennebichler, J. Gesperger, B. Baumann, D. Harper, C. Merkle, A. Lichtenegger.

Principal Investigator


Bernhard Baumann

Postdocs


Antonia Lichtenegger	Conrad Merkle

PhD students


Pablo Eugui	Johanna Gesperger

Master students


Maryam Salehi Ravesh

Alumni

Marco Augustin
Stanislava Fialová
Danielle J. Harper
Konrad Leskovar
Martina Muck

Zoe Neuburger
Carlos Reyes
Johannes Schirmer
Simon Strehn
Matthias Wechdorn

Projects

Optical imaging of ocular pathology in Alzheimer’s disease – OPTIMALZ (2015)
European Research Council
Preclinical imaging of the rodent eye with multi-functional optical coherence tomography (2013-2018) Austrian Science Fund (FWF)

Publications

Selected peer-reviewed publications

Complete List of Publications

C. W. Merkle, M. Augustin, D. J. Harper, B. Baumann, "Indocyanine green provides absorption and spectral contrast for optical coherence tomography at 840 nm in vivo," Optics Letters 45, 2359-2362 (2020).
P. Eugui, D. J. Harper, S. Kummer, A. Lichtenegger, J. Gesperger, T. Himmel, M. Augustin, C. W. Merkle, M. Glösmann, B. Baumann, "Three-dimensional visualization of opacifications in the murine crystalline lens by in vivo optical coherence tomography," Biomedical Optics Express, 11(4), 2085-2097 (2020).
M. Augustin, D. J. Harper, C. W. Merkle, M. Glösmann, C. K. Hitzenberger, B. Baumann, "Optical Coherence Tomography Findings in the Retinas of SOD1 Knockout Mice," Translational Vision Science & Technology 9(4), 15 (2020).
D. J. Harper, M. Augustin, A. Lichtenegger, J. Gesperger, T. Himmel, M. Muck, C. W. Merkle, P. Eugui, S. Kummer, A. Wöhrer, M. Glösmann, B. Baumann, "Retinal analysis of a mouse model of Alzheimer’s disease with multicontrast optical coherence tomography," Neurophotonics, 7(1), 015006 (2020).
B. Baumann, C. W. Merkle, R. A. Leitgeb, M. Augustin, A. Wartak, M. Pircher, C. K. Hitzenberger, "Signal averaging improves signal-to-noise in OCT images: But which approach works best, and when?," Biomedical Optics Express 10, 5755-5775 (2019).

Completed Theses

PhD theses

Harper, Danielle J., Depth-resolved multi-contrast retinal imaging with high axial resolution, PhD thesis, Medical University of Vienna, 2020.
Lichtenegger, Antonia, Multimodal visible light optical coherence microscopy for ex vivo brain imaging, PhD thesis, Medical University of Vienna, 2020.
Augustin, Marco, Multi-Functional Optical Coherence Tomography for Preclinical Retinal Imaging, PhD thesis, Medical University of Vienna, 2018.
Fialová, Stanislava, High resolution polarization sensitive optical coherence tomography for ocular imaging in small animals, PhD thesis, Medical University of Vienna, 2016.

Master and diploma theses

Neuburger, Zoe, Diagnostic validity of visible light optical coherence microscopy data compared to histological data taken from Alzheimer’s disease mouse brain tissue, MD thesis (co-supervised by Antonia Lichtenegger and Bernhard Baumann), Medical University of Vienna, 2019.
Wechdorn, Matthias, In vivo Imaging von retinalen Neovaskularisationen im Mausauge, MD thesis (co-supervised by Marco Augustin and Bernhard Baumann), Medical University of Vienna, 2019.
Strehn, Simon, Mehrschichtige Streuphantome für die optische Kohärenztomographie, MSc thesis (co-supervised by Martin Gröschl and Bernhard Baumann), TU Vienna, 2017.
Schirmer, Johannes, Quantitative Messung der Melaninpigmentierung in Rattenaugen, MD thesis, Medical University of Vienna, 2016.